Abstract: Through the investigation on Ecological management of Protosalanxchinensis and H. nipponensis in Erhai Lake in 2020,the regional differences of Protosalanxchinensis and H. nipponensis were revealed. The overall yield of Protosalanxchinensis showed a trend of north > south > east. The overall yield of H. nipponensis showed a trend of Shangguan Town > Taihe Town > Yinqiao Town > Wanqiao Town > Xizhou Town > Wase Town > Haidong Town > Dali Town > Manjiang Town > Shuanglang Town. Therefore,the regional differences of H. nipponensis were small when comparing the total yield of Protosalanxchinensis.