Abstract: Taking the provincial middle school in Nanta province of Laos as the object,through the design and implementation of domestic sewage treatment system,sewage collection system and reclaimed water reuse system,the rainwater and sewage separation of middle school drainage system was realized,and the sewage collection rate was more than 70%. It is expected that the sewage treatment of Nanta provincial middle school would play a demonstration role in the future domestic sewage treatment in Nanta province.